At the molecular level, gene duplication often produces novelty in a lineage. This process provides another evolutionary pathway by which a protein can switch functions, without loss of the original function. What analytical approach helped the most to answer the question of evolution in the aldosterone-M receptor pair in the study of Jamie Bridgham and her colleagues

Answers

Answer 1

Answer:

Bridgham et al. (2006) showed that the interaction between a steroid hormone (aldosterone-M) and its receptor (mineralocorticoid) evolved by Darwinian gradualism. In this work, the authors demonstrated  a primitive affinity between the hormone and its receptor that was initially present in chemically similar but more ancient ligands. This result has implications in understanding the association between gene duplication and the evolution of hormone signaling pathways. For example, in invertebrates, this work reinforces the importance of gene duplication in the existing interaction between paralogous glucocorticoid receptors and their receptor mineralocorticoid genes that were derived from duplication (Thornton 2001).

The publications above cited are the following:

J.T. Bridgham, S.M. Carroll, and J.W. Thornton (2006). Evolution of hormone-receptor complexity by molecular exploitation. Science, 312(5770), 97-101.

JW Thornton. Evolution of vertebrate steroid receptors from an ancestral estrogen receptor by ligand exploitation and serial genome expansions, Proc Natl Acad Sci USA (PNAS), 2001, vol. 98 10 (pg. 5671-5676).


Related Questions

What is the purpose of a Punnett square?

Answers

Answer:

A Punnett square is a diagram used to determine the statistical likelihood of each possible genotype of the offspring of two parents for a given trait or traits. Reginald Punnett was applying the laws of probability to work pioneered by Gregor Mendel in the mid-1800s.

hope that helps love!

Answer:

The Punnett square is a square diagram that is used to foretell the genotypes of a particular cross or breeding experiment. The diagram is used by biologists to determine the possibility of an offspring having a precise genotype.

Explanation:

If the surface soil is saturated and precipitation increases, there will be

a. a decrease in the surface elevation of the lake
b. a decrease in the amount of groundwater
c. an increase in the rate of capillarity
d. an increase in the amount of runoff

Answers

The correct answer is D. An increase in the amount of runoff

Explanation:

Surface soil is considered to be "saturated" if soil cannot absorb more water as all pores in it are already filled. This can occur when there has been a lot of precipitation, or the retention of soil is low. Additionally, when soil is saturated and it is in contact with more water (for example, if precipitation increases) the water will not be absorbed by the soil but will flow to other areas, which is known as runoff. Thus, if the surface soil is saturated and there is precipitation, there will be an increase in the amount of runoff.

Answer

it is (option D) Have A Fantastic Day eaglestar446 on YT

Explanation:

the guy above me is correct :)

to occur where faults are 1) Earthquakes are located. 3- less likely more likely

Answers

Answer & Explanation:

Earthquakes can strike at any location on Earth and at any point of time. However, some parts of the Earth are more prone to earthquakes than others. Earthquakes happen along the edges of tectonic plates and fault lines and there are three large zones on our planet which are most susceptible to earthquakes.:-)

What is stored in carbon bonds?

Answers

Energy is stored in carbon bonds, The type of energy stored in carbon bonds can be either potential or chemical energy.

Answer:

energy

Explanation:

match each term to the example that describes it.
-three populations of insects from neighboring regions are able to interbreed.
-a population of a spider species has a wide variance in individual traits.
-researchers in the amazon region found 100 different types of ants living in one tree.
-sea otters eat sea urchins, preventing urchin overpopulation.
pairs:
-genetic diversity
-keystone species
-species diversity
-ecosystem diversity

Answers

genetic diversity - a population of a spider species...
keystone species - sea otters eat sea urchins...
species diversity - researchers in the amazon...
ecosystem diversity - three populations of insects...
got these ALL right on edmentum‼️

Answer:

genetic diversity - a population of a spider species

keystone species - sea otters eat sea urchins

species diversity - researchers in the amazon

ecosystem diversity - three populations of insects

Explanation:

plato

Which of the following is NOT a reason bacteria are good for genetic engineering? A. Their DNA accepts new genes more easily than Eukaryotes. B. DNA is easy to access and modify. C. They replicate very quickly. D. Plasmids can be engineered easily to produce proteins.

Answers

Answer:

D

Explanation:

"Scientists insert genes into loops of DNA called plasmids using natural processes and technological innovations. They can then introduce plasmids into bacteria or other cells, which replicate the inserted genes or induce the cells to produce such valuable proteins as human insulin and growth hormone."

The following is not a valid reason that indicates bacteria are good for genetic engineering:

Plasmids can be engineered easily to produce proteins.

Thus, the correct option is D.

What is Genetic engineering?

Genetic engineering may be defined as a methodology that utilizes laboratory-based technologies and equipment that support in the alteration of the DNA makeup of an organism.

A plasmid is a genetic structure that mediates the translocation of the genetic material of one organism to another for the purpose of modification.

Examples include insulin production, hormone synthesis, increase productivity in plants, etc.

The Plasmid is inserted into bacterial cells when the genetic material of the experimental organism is successfully employed. This process does not deal with the reason that bacteria are good for genetic engineering.

Therefore, the correct option is D.

To learn more about Genetic engineering, refer to the link:

https://brainly.com/question/2780091

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viral envelopes are made of​

Answers

Answer:

fats and proteins.  

Explanation:

_________3. In photolysis, some of the energy captured by chlorophyll is used to split:
A. H2O B. NADPH C. ATP D. CO2

Answers

Answer:

A) H2O

Explanation:

This helps us produce oxygen and hydrogen. This is the oxygen that you breathe because we have always heard plants give us oxygen and this is how they do it

distinguish between taxonomy and taxon​

Answers

Answer:

taxonomy is  the branch of biology which deals with classification.

the groups into which organisms are classified are known as taxonomic categories or taxa (plural taxon)

Explanation:

i hope it will help you

Develop a hypothesis to explain why you think eurypterids developed legs even though they lived on the ocean floor.

Answers

I think that since it lives on the ocean floor, at the deepest of the ocean. So anyway, the fin on the Eurypterids is still necessary but not that much, since they live on the ocean floor. Their movements mostly on the ocean floor. So fin would not help them "stick" to the floor. Also there are still gravity acts on the Eurypterids and the feet would help them move faster. Hope this helps.

Hey please help plzz:)

Answers

Answer:

A is the correct answer of this question

Explanation:

I hope this helps

does tracheids have protoplasts or not​

Answers

Answer:

no

Explanation:

tracheids doesn't have protoplasts

4. What do complement proteins do?
O They heal tissue.
They transport hormones.
O They cause fever.
O They signal phagocytes.

Answers

Answer:

They signal phagocytes.

Explanation:

hope this helps

The English system issues as the international system of measurement true or false

Answers

Answer:false

Explanation:

Name the ionic compound PbCO3

Answers

Answer:

lead carbonate

Explanation:

The ionic compound PbCO3 is called lead(II) carbonate.



Let's break down the name to understand it better:

1. The symbol "Pb" represents the element lead.
2. "CO3" is the chemical formula for carbonate, which is a polyatomic ion consisting of one carbon atom and three oxygen atoms.

To name the compound, we use the Stock system for naming compounds containing transition metals like lead.

1. The Roman numeral "(II)" indicates the charge of the lead ion in the compound. In this case, lead has a +2 charge. The Roman numeral helps differentiate between different possible charges of the metal ion.
2. The word "carbonate" represents the polyatomic ion CO3.

Therefore, the name of the ionic compound PbCO3 is lead(II) carbonate.

To know more about lead(II) carbonate:

https://brainly.com/question/4313567

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بي
As the human population grows, what happens to our natural-resource requirements?
They increase.
They decrease.
They do not change.
They go in cycles

Answers

Answer:

They decrease.

Hope this helps.

Answer:

They Increase

Explanation:

Just took the test.

Which processes are associated with the formation of tornadoes select three options

Answers

Answer:

the answer is D

Explanation:

_________7. During strenuous exercise, skeletal muscles use up ___________ and produce large amount of ________, which causes pain and fatigue in the muscle.
A. Oxygen, lactic acid C. CO2, pyruvic acid
B. Pyruvic acid, lactic acid D. Pyruvic acid, CO2

Answers

Answer:

A. Oxygen, lactic acid

What is the utilized equipment for studying fluorescence-labelled cells?

Answers

Answer:

The equipment for studying fluorescence-labelled cells is called the Fluorescence microscope. The process of using this equipment for studying fluorescence-labelled cells is called Fluorescence microscopy.

This equipment is very much in use with regards to the study of how molecules are distributed within a cell.

Cheers!

If the interference value is 1, then what is the probability of recombination between genes A and B if: 1.There is a recombination between genes B and C, where the gene order is A-B-C; 2.The recombination fraction between A and B is 0.05; 3.The recombination fraction between B and C is 0.45?
A. 0.45.
B. 0.05.
C. 1.00.
D. 0.15.
E. 0.0.

Answers

Answer:

E. 0.0.

Explanation:

The measure of crossing over  coincidence interrelatedness between one cross over and another in a given pair of chromosome is known as what is called Interference.

Given that :

the interference value = 1

The probability of recombination between genes A and B is zero i.e 0.0 because:

when another gene co-occur with a particular gene during cross over, the coefficient of coincidence decreases. We know that the interference is maximum at 1, we can say it ranges from 0-1; now that two recombination is taking place in two genes,the probability is likely to decrease from 1 to 0.0

Similarly;  Since  the probability of recombination is taking place  between two genes i.e genes A and B. Then  there is no probability of  double crossover when interference value = 1 but when it is zero there is probability of double crossover to occur. With that being said, the probability of recombination between genes A and B is 0.0

Why the rainforest in Costa Rica is not rich with plants? Remember to use scientific language

Answers

Answer:

Deforestation is the major problem causing lack of rich species in Costa Rica. This is due to over grazing by cattle.This may lead to flooding which affect fertility of the soil.These animals graze on  the plants without regulations,and cause erosion as their hoofs percolate the soil,  further reducing soil fertility.

In addition to sustain the beef production,  trees were fell to for cattle ranching.This ultimately contributed to loss of the forest species.

Banana plantation is an  additional factor.Forest were cleared to cultivate banana, which affects forest population.

Explanation:

The tertiary structure of proteins arise due to ?

Answers

Answer:

Side Chain or R group interactions

Explanation:

Tertiary structures of proteins is highly influenced by the interaction between the R-groups of amino acids which may form hydrogen bond, convalent bonds, london dispersion forces etc) to give the overall three-dimensional structure of a polypeptide

The Eocene period exists in Earth’s history around 34 MYA. What could a scientist do to determine what era the Eocene period belongs to on the geologic time scale?

Answers

Answer:

To understand what era the Eocene period belongs to on the geologic time scale, the scientist would have to examine the Cenozoic era to understand all information related to it.

Explanation:

First, let's start with an explanation of terms.

MYA simply means Millions of Years Ago Time Scale is a sequence or organisation of events which is used as a yardstick to measure the duration of history or how long the earth has existed. Eocene Period refers to the geological epoch that lasted from about fifty-six to approximately forty MYA. It is also defined as the second epoch of the Paleogene Period within the modern Cenozoic Era.  

Given the definition of the Eocene Period, to understand what era an Eocene period belongs to, the person must carefully study the Cenozoic era.

Cheers!

Answer:

b

Explanation:

The word centripetal means "center-

Answers

Answer:

petus ‘seeking’

Explanation:

I think, I'm pretty sure. ;)

I hope this helped

Answer:

Moving or trending to move toward a center.

Explanation: centripetal is an adjective describing a force that brings things toward the center, not unlike the force of a black hole..

Suppose that a population composed of 100 individuals existed on an island in the Caribbean Sea. Two different alleles of the A gene were present in this population ( a1 and a2 ) at equal frequency. The following events occurred to this unlucky population. Determine what evolutionary force (mutation, migration, drift, or selection) is represented by each event. In addition, tell the effect of each eventon the genetic composition of the population.A) A devastating fire caused the death of 10 individuals.
B) A disease swept through the island and killed 13 individuals. The a1 confers resistance to the disease.
C) A disease swept through the island killing 13 individuals. Neither a1 nor a2 confers resistance to the disease.
D) A boat containing individuals from a different island containing a1, a2, and a3 alleles landed at the island.
E)The leader (whose genotype is a1a1) declared that only individuals with the a1 have the right to be on the island and mate. All a2, a3 individuals moved to another island.
F) A man stumbles upon a barrel that has spilled its contents on some rocks. Unknown the to man, who cannot read, the barrel says "Radioactive". He decides to bring one of the new glowing rocks home to show his wife and puts it in his pants pocket.Some of their babies had an a4.

Answers

Answer:

Explanation:

D) A boat containing individuals from a different island containing a1, a2, and a3 alleles landed at the island.

This is an example of migration. It is the movement of an organisms into a particular place or habitat. It increase the population of its new environment and decrease the population of the environment it migrated from.

E)The leader (whose genotype is a1a1) declared that only individuals with the a1 have the right to be on the island and mate. All a2, a3 individuals moved to another island.

This is example of selection. Selection is done in a large population to select traits with desired characteristics. Selection helps to have individual with the best features.

F) A man stumbles upon a barrel that has spilled its contents on some rocks. Unknown the to man, who cannot read, the barrel says "Radioactive". He decides to bring one of the new glowing rocks home to show his wife and puts it in his pants pocket.Some of their babies had an a4.

This is an example of mutation. It a sudden heritable change in the genome of an organism. it can be caused by exposure to radioactive material. Mutation can have a detrimental effect on individual carrying it or useful.

A) A devastating fire caused the death of 10 individuals

Drift- Genetic drift leads to the loss of genotype that are less frequently perpetuated or less occuring and are selected against.

B) A disease swept through the island and killed 13 individuals. The a1 confers resistance to the disease.

Selection- they have selective advantage of been resistance to disease.

It there a plastic that you can see through AND BREATHE THROUGH???

Answers

Mandibule plastic is the one

which type of bond represent a weak chemical bond

Answers

Answer:

hydrogen bonds and london dispersion force and van der walls forces

Explanation:

these bonds represent weak bond because their bond energy is very less __kj/mole.

In what part of the day do plants produce more carbon dioxide and oxygen

Answers

Answer:

During the day in the light reactions of photosynthesis

Explanation:

During the day, as there isn’t light for it to take in at night

can people misdiagnose themselves with the flu

Answers

Answer:

Yes

Explanation:

Answer:

yes

Explanation:

the semtoms are very close to a common cold so a lot of people that don´t truly know the sign can misdiagnose themself´s

Explain the relationship between mutations, adaptations,
natural selection, and extinction.

Answers

Answer:

Adaptations result from random mutations in the genes of organisms. Depending on the environment, these adaptations may be favorable or unfavorable. If an adaptation is favorable, it is selected by nature and, over time, more and more organisms in a population will have it. If the environment changes so much that the adaptations of a species are no longer enough for the species to survive, extinction will occur.

Explanation:

Answer:

this person is correct^

Explanation:

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Problems with (or leakages from) the money creation process would include an increase in the reserve requirement. unwillingness of borrowers to obtain loans from banks to invest in factories or expansion of the firm. a decrease in the reserve requirement. an increase in the federal funds rate. a decrease in the federal funds rate. Noah's water bottle contains more than 1 quart of water but less than LaTeX: 1\frac{1}{2}1 1 2 quarts. Let w be the amount of water in Noah's bottle, in quarts. Select all the true statements.Group of answer choices Question 3 of 171 PointHow did the media help Bill Clinton attract young voters?O A. Reports about him were like entertainment rather than hard news.O B. He appeared on television shows that young people watched.O c. His television debate subjects were of interest to young people.O D. Young people could see firsthand that he was relatively young.SUBMIT will mark brainliest!! solve & simplify the following equation: x+5x=0 If 3^x=10, what is the value of 3^x-3? A. 10/3 B. 10/9 C. 10/27 D. 27/10 What type of figurative language is the author using Why are natural disasters in the west coast more dangerous than the ones in the East Coast +7-8/3=-5/2 please help me with this please pleaseplease Write a paragraph that evaluates Odysseuss qualifications as an epic hero. Only do question 1650 pointsTopic: Percentage I really need help with this please help best aswer gets brainliest Answer Is not Cplease help Luis uses cubes to represent each term of a pattern based on a recursive function. The recursive function defined is f(n + 1) = f(n) + 4, where n is an integer and n 2. The number of cubes used in each of the first two figures is shown below. How many cubes does Luis use in the third, fourth, and fifth figures of the pattern? Fill in the blanks. During his hike, Milt drank 1 liter of water and 1 liter of sports drink. How many milliliters of liquid did he drink? Solve: log4(7t+2)=2 Using the periodic table as a reference, which elements could bond to form a compound most like NaCl?Question 3 options:Hydrogen (H) and Oxygen (O)Potassium (K) and Fluorine (F)Magnesium (Mg) and Iodine (I)Lithium (Li) and Sulfur (S) Simplify each and state the excluded values p+4/p^2+6p+8 Simplify 7N - 2N + 3P + 2P.5N + 5P10N + 10P10NP Which angles are right?NDdohetMCheck all that apply.A. KLJIN B. EFH1 C. AGFED. ZMLK PLS CAN SOMEONE HELP PLS WILL GIVE BRAINLIESTTHE FIRST TWO PICTURES ARE NUMBER ONE AND THE THIRD ONE IS FOR QUESTION 22. Use the diagram below to find x